Carboxylic acids and derivatives
Aobchem 4-Fluoro-3 5-dimethylbenzamide | ≥97% | CAS 886501-71-9 | C9H10FNO | 500mg
4-Fluoro-3 5-dimethylbenzamide | ≥97% | CAS 886501-71-9 | C9H10FNO | 500mg
Aobchem N-(2 4-dichlorophenyl)acetamide | ≥97% | CAS 6975-29-7 | C8H7Cl2NO | 500mg
N-(2 4-dichlorophenyl)acetamide | ≥97% | CAS 6975-29-7 | C8H7Cl2NO | 500mg
Aobchem 2-(4-Formylphenoxy)acetonitrile | ≥95% | CAS 385383-45-9 | C9H7NO2 | 1g
2-(4-Formylphenoxy)acetonitrile | ≥95% | CAS 385383-45-9 | C9H7NO2 | 1g
Aobchem N-(2 4-dichlorophenyl)acetamide | ≥97% | CAS 6975-29-7 | C8H7Cl2NO | 250mg
N-(2 4-dichlorophenyl)acetamide | ≥97% | CAS 6975-29-7 | C8H7Cl2NO | 250mg
Aobchem 2-(4-Formylphenoxy)acetonitrile | ≥95% | CAS 385383-45-9 | C9H7NO2 | 5g
2-(4-Formylphenoxy)acetonitrile | ≥95% | CAS 385383-45-9 | C9H7NO2 | 5g
Apexbio Technology LLC Methiothepin maleate 19728-88-2 50mg
Methiothepin maleate (CAS 19728-88-2) is a small molecule antagonist targeting serotonin receptors including 5-HT1 5-HT6 and 5-HT7 subtypes By inhibiting serotonin autoreceptors it modulates downstream signaling pathways associated with neurotransmission This compound has been widely utilized in neuroscience research to investigate the regulatory mechanisms of serotonergic signaling and to explore the pathophysiology of related neurological disorders Its ability to selectively block multiple serotonin receptor subtypes makes it a valuable tool for delineating complex neural pathways and receptor functions in experimental models
Medchemexpress LLC Sulforhodamine 101 DHPE | 187099-99-6 | >95.0% | 1381.84 | C74H117N4O14PS2 | 1MG
Sulforhodamine 101 DHPE is a red fluorescent phospholipid probe created by conjugating dipalmitoyl phosphoethanolamine to sulforhodamine 101. It readily incorporates into lipid bilayers and is used for membrane imaging, monitoring probe colocalization in liposomes, and detecting protein-ligand interactions on supported bilayers. The dye exhibits excitation/emission peaks near 586/605 nm and is supplied as a powder with recommended cold storage.
Gold Biotechnology Inc TCEP-HCl 10 g
TCEP (Tris (2-Carboxyethyl) phosphine Hydrochloride) is an odorless reducing agent suitable for protein applications and in the preparation for electrophoresis. TCEP is water soluble, is stable in a variety of solutions and is particularly useful in the labeling of cysteine residues with maleimides, preventing the cysteines from forming disulfide bonds.
Sigma Aldrich Fine Chemicals Biosciences Suramin sodium salt 98 TLC25MG
Suramin is an antiparasitic drug which blocks endothelial cell proliferation and increases tyrosine phosphorylation of many signalling proteins. It is associated with urticaria paresthesias vomitingnbspand neurologic toxicity. Suramin is used to treat trypanosomiasis and onchocerciasis. It functions as an inhibitor of heparanasenbspand also exhibits anti-AIDS (acquired immunodeficiency syndrome) property.
Apexbio Technology LLC Simvastatin (sodium salt)(Synonyms: Simvastatin sodium, Simvastatin sodium salt, Sodium simvastatin, Synvinolin sodium), 25mg, CAS: 101314-97-0.
Simvastatin (sodium salt) (CAS 101314-97-0) is an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase a critical enzyme controlling the rate-limiting step in cholesterol biosynthesis It binds with high affinity to HMG-CoA reductase exhibiting a Ki of approximately 0 12 nM In hepatocyte-derived Hep G2 cells simvastatin demonstrated potent suppression of cholesterol biosynthesis reducing the incorporation of radiolabeled acetate into sterols (IC50 15 nM) Animal studies with orally administered simvastatin indicated marked reduction in plasma cholesterol levels validating its utility in experimental models exploring cholesterol regulation and lipid metabolism
Apexbio Technology LLC (+)-MK 801 Maleate 77086-22-7 10mg
( )-MK 801 Maleate is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor exhibiting a Ki value of approximately 30 5 nM By blocking the NMDA receptor-mediated ion channel MK 801 disrupts glutamate-associated excitatory neurotransmission In experimental models MK 801 demonstrates anticonvulsant and anxiolytic properties through modulation of NMDA receptor activity This compound readily penetrates the central nervous system binding reversibly and region-specifically to cortical and hippocampal membranes MK 801 effectively inhibits NMDA-triggered depolarization responses in neuronal preparations making it applicable in studies focused on epilepsy excitotoxicity and neuronal signaling pathways
Apexbio Technology LLC CA-074 Me 147859-80-1 10mM (in 1mL DMSO)
CA-074 Me (CAS 147859-80-1) is a cell-permeable methyl ester derivative of CA-074 functioning primarily as a selective inhibitor of cathepsin B It exhibits potent inhibitory activity against cathepsin B (IC50 36 3 nM) In cultured human gingival fibroblasts CA-074 Me effectively suppresses cathepsin B activity while moderately reducing combined cathepsin B and L activities Under strong reducing conditions (e g presence of DTT or GSH) CA-074 Me inhibits cathepsin L substantially Thus it is widely utilized in biomedical research to study lysosomal enzyme functions and roles of cathepsins in cellular processes
Cayman Chemical Fumonisin B1, Purity: ≥95%, CAS: 116355-83-0, 1 mg
A mycotoxin; inhibits ceramide synthase (IC50 = 0.1 µM for the rat liver enzyme); induces DNA fragmentation and apoptosis in CV-1 cells at 5 and 25 µM, respectively; cytotoxic to primary rat hepatocytes; induces hepatocyte nodule formation, a marker of cancer initiation, in rats at 500 mg/kg for 21 days; has been detected in corn and corn-based foods and livestock feeds
Sigma Aldrich Fine Chemicals Biosciences NADP Disodium salt
Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. The NADPH/NADP ratio regulates the intracellular redox potential thereby influencing metabolic reactions in vivo.
Sigma Aldrich Fine Chemicals Biosciences TrizmaR base BioUltra for1KG
Tris is an established basimetric standard and buffer used in biochemistry and molecular biology. It may be used by itself as a buffer or as a component of mixed buffer formulations such as Tris-EDTA (TE) buffer Tris-acetate-EDTA (TAE) buffer Tris-borate-EDTA (TBE) buffer etc. It is pure essentially stable relatively non-hygroscopic and has a high equivalent weight. The BioChemika quality is for the usual biochemical applications. The products designated as BioChemika Ultra grade are suitable for different applications like purification precipitation crystallization and other applications which require tight control of elemental content. Trace elemental analyses have been performed for all qualities. The molecular biology qualities are also tested for absence of nucleases and the luminescence quality spectroscopic tests are performed.